Distinguishing Multiple CCK Receptor Subtypes.
نویسندگان
چکیده
منابع مشابه
Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes.
Although nicotinic agonists can modulate sensory transmission, particularly nociceptive signaling, remarkably little is known about the functional expression of nicotinic acetylcholine receptors (nAChRs) on primary sensory neurons. We have utilized molecular and electrophysiological techniques to characterize the functional diversity of nAChR expression on mammalian dorsal root ganglion (DRG) n...
متن کاملDistinct subtypes of cholecystokinin (CCK)-containing interneurons of the basolateral amygdala identified using a CCK promoter-specific lentivirus.
The basolateral amygdala (BLA) is critical for the formation of emotional memories. Little is known about the physiological properties of BLA interneurons, which can be divided into four subtypes based on their immunocytochemical profiles. Cholecystokinin (CCK) interneurons play critical roles in feedforward inhibition and behavioral fear responses. Evidence suggests that interneurons within a ...
متن کاملTriple-negative breast cancer: distinguishing between basal and nonbasal subtypes.
PURPOSE Triple-negative (TN; estrogen receptor, progesterone receptor, and HER-2 negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome and lack the benefit of targeted therapy. It is widely perceived that BLBC and TN tumors are synonymous and BLBC can be defined using a TN definition without the need for the expression of basal markers. EXPERIMENTAL DESIGN We h...
متن کاملDistinguishing Subtypes of Multiword Expressions Using Linguistically-Motivated Statistical Measures
We identify several classes of multiword expressions that each require a different encoding in a (computational) lexicon, as well as a different treatment within a computational system. We examine linguistic properties pertaining to the degree of semantic idiosyncrasy of these classes of expressions. Accordingly, we propose statistical measures to quantify each property, and use the measures to...
متن کاملMetabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons.
Metabotropic glutamate receptor (mGluR) modulation of voltage-gated Ca2+ channels was examined in isolated deep layer frontoparietal cortical neurons under conditions designed to isolate calcium-independent modulatory pathways. Trans-1-aminocyclopentane-1,3-dicarboxylate (t-ACPD), a nonspecific mGluR agonist, produced rapid and reversible inhibition of Ca2+ channels. This effect was mimicked by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 1994
ISSN: 0077-8923,1749-6632
DOI: 10.1111/j.1749-6632.1994.tb44055.x